Houston’s No-Fenol (90 capsules)


Houston’s No-Fenol (90 caps)


  • Unique Formulation to Assist in Digestion of Phenolic Food
  • High Amounts of Xylanase and Cellulase Enzymes
  • Phytase present to increase the availability of minerals and nutrients

No-Fenol was developed by Dr. Devin Houston, the founder of Houston Nutraceuticals (HNI), in response to requests for a product that would allow one to eat fruits and vegetables without the problems thought to be associated with some phenolic compounds. Initial responses from many indicate that No-Fenol can allow the addition of these foods to the diet without complications.


All plants contain some degree of phenolic compounds (sometimes called "phenols"). The phenol structure itself is found everywhere in nature, and is essential to many of life's processes. Current thinking by many is that some have difficulty in the processing of phenolic compounds. The research literature indicates that some phenolic compounds are modified by the addition of carbohydrate groups to their structures, which may inhibit their crossing into cells and being metabolized. The current hypothesis for why No-Fenol may help is through the ability of the enzymes in this product to remove the carbohydrate groups from the phenols, thus allowing normal processing by the detoxification pathways. There is no evidence that No-Fenol directly modifies phenolic structures. Rather, the success of No-Fenol in allowing the addition of phenolic foods back into the diet may result in a re-evaluation of the basis of the phenol "problem".


Xylanase is the major component of No-Fenol, and is an enzyme used to breakdown the structural components of plant cell walls, which are primarily very complex carbohydrates. Xylanase is used in the juice industry to extract more juice from fruit pulp fibers. At least one reference indicates that polyphenolic compounds are actually increased by the presence of xylanase. Based on this reference and the fact that No-Fenol has allowed "phenol-sensitive" individuals to ingest phenolic foods, Houston Enzymes now believes that the phenol issue is much more complex than previously thought, and may not be due so much to the presence of phenols as to the specific structure of these phenols.


Foods rich in polyphenols include:

  • brightly colored fruits and vegetables
  • red wine
  • coffee
  • black and green teas
  • spices
  • dark chocolate


Reported Side Effects

In some cases, stools were softer and less formed, which may be a result of the enzymes decreasing the viscosity of the intestinal contents, as noted in animal studies.


Contraindications for Enzyme Supplementation

This product may not be appropriate for those with known allergies to Aspergillus enzyme proteins, though non-specific mold allergies do not necessarily preclude use of fungal enzymes. Consult your medical doctor for further advice, and err on the side of caution. Those with known anaphylactic allergic reactions to fungal proteins should NOT ingest fungal-derived enzymes.



Suggested Dosage: 1 capsule with phenolic foods, but not necessarily with every meal. No-Fenol is suggested primarily for those with known intolerances to phenolic compounds. Some have found satisfactory results with once or twice per day dosing, indicating that optimal dosing may be dependent upon many factors. No upper limit has been established for enzyme dosing, and animal studies found no toxicity at dosing as high as 80,000 FXU per kilogram of body weight per day for 13 weeks.



Each capsule contains:


Supplement Facts

Serving size: 1 capsule %DV
Servings Per Container: 90  

Proprietary enzyme blend

288 mg



32,000 XU


CereCalase™ hemicellulase, beta-glucanase, phytase

75 mg


*Daily Value not established.

Other Ingredients: Vegetable capsule, (cellulose and water) , microcrystalline cellulose, and medium chain triglycerides.


Caution: The MCT is derived from palm or coconut oil.


The production process used to manufacture the enzymes found in this product utilizes fermentation materials that are derived from or contain the allergens listed below.  While these fermentation materials should be either consumed during fermentation or removed from the enzyme during additional enzyme isolation steps, minute traces of these allergens may be left in the final enzyme product.  While these traces are expected to be below the limits of detection for standard ELISA based allergen testing methods, there is no guarantee the complete absence of these following allergens:  Wheat

CereCalase™ is a registered trademark of National Enzyme Company.

These statements have not been evaluated by the FDA. This product is not intended to diagnose, cure, treat, or prevent any disease.