Houston’s AFP Peptizyde (90 capsules)


Houston’s AFP Peptizyde (90 caps)


·         Enzyme combination for digestion of food protein

·         Supports breakdown of dairy and wheat proteins

·         Includes Dipeptidyl Peptidase IV (DPP IV) enzyme activity

·         Safe, non-toxic supplement for GFCF Diet


AFP Peptizyde is a combination of three different enzymes that break down food proteins.  These enzymes are isolated and purified from fungal sources. The combination of these specific enzymes allows much more efficient means of quickly and thoroughly breaking proteins into smaller components.  The enzymes in AFP Peptizyde work only on food proteins, not carbohydrates, fats, or other compounds, and do not interfere with medications or other supplements (unless they are also proteins, which is extremely unlikely). AFP Peptizyde may be used in combination with other enzyme products.


The enzyme dipeptidyl peptidase IV, or DPP IV, is able to break down and inactivate the exorphin peptide casomorphin from dairy. However, for maximal protein breakdown, it is not useful alone, and should be combined with other proteases with different and less stringent peptide bond specificity. For this reason, AFP Peptizyde contains two other fungal-derived proteases with high activity in acid conditions. These enzymes are present in AFP Peptizyde in high amounts for the purpose of quickly hydrolyzing (breaking down) proteins while the food is still in the stomach. The ability of AFP Peptizyde enzymes to withstand the low pH of the stomach and remain active under acidic conditions allows breakdown of casein and gluten prior to entrance into the small intestine. Casein and gluten, in the presence of pancreatic enzymes in the small intestine, can produce exorphin peptides that may be readily absorbed from the intestine (these peptides are not absorbed from the stomach). AFP Peptizyde supplements the "normal" breakdown of casein, gluten, and other food proteins such that the exorphin peptides are less ikely to be produced.  The additional acid-stable protease activity provided by AFP Peptizyde allows protein break down to occur earlier and more thoroughly since very little protease activity exists in the stomach. 


AFP Peptizyde contains only those enzymes needed for protein hydrolysis. No other enzymes, such as those for carb and fat digestion, have been added. This allows one to customize enzyme supplementation to their specific dietary needs. Another advantage to this approach is that less potential exists for intolerance reactions due to additional and perhaps unnecessary enzyme proteins. Also, by using only three enzyme blends in AFP Peptizyde, larger amounts of each enzyme can be added per capsule. This ensures that more breakdown of food protein can take place in the short time that food is in the stomach.

Another advantage to this approach is that less potential exists for intolerance reactions due to additional and perhaps unnecessary enzyme proteins.  Also, by using only three enzymes blends in AFP Peptize, larger amounts of each enzyme can be added per capsule.  This ensures that more breakdown of the food protein can take place in the short time that food is in the stomach.

AFP Peptizyde is NOT intended to allow gluten back in the diet for those with celieac disease.  Anyone with celiac disease should maintain a gluten-free diet.  No supplement will allow those with celiac disease to ingest gluten.

AFP Peptizyde is recommended for high protein diets, and dosing may be increased for those meals.  No more than 3 capsules are recommended to be taken at any one time.

Contraindications for Enzyme Supplementation

These enzymes should  be used with care under the following circumstances: active stomach or duodenal ulcers, severe bowel inflammation (characterized by blood in stools), hemophilia and other bleeding disorders, or within a week of scheduled surgery. This product may not be appropriate for those with known allergies to Aspergillus enzyme proteins, though non-specific mold allergies do not necessarily preclude use of fungal enzymes. Consult your medical doctor for further advice, and err on the side of caution. Those with known anaphylactic allergic reactions to fungal proteins should NOT ingest fungal-derived enzymes.


Suggested Dosage:  Take 1  capsule before meals and snacks.  Contents can be opened and mixed with food or beverage.  Use care not to inhale enzyme powder.   For the infrequent and large food challenge, as much as 3 capsules may be given but no further benefits will occur with higher dosing. Maximum consistent dosing per day is suggested to be no more than 9 capsules per day. No upper limit has been established for enzyme dosing.  Most find using 1 to 3 capsules per meal adequate, and most likely no further benefits will occure with higher dosing.  We encourage some experimentation to find the dose that best helps each person. 


Each capsule contains:                                             

Supplement Facts

Serving size

1 Capsule


Servings per container 90  

Proprietary Enzyme Blend

320 mg


   Peptidase (source DPP IV) 55,00 HUT *
      DPP IV 1,100 DPU


   Protease 4.5

25,000 HUT


   Protease 6.0

25,000 HUT


* Daily Value not established.

Other Ingredients:  Capsule (hypromellose and water), microcrystalline cellulose and medium chain triglyceride powder.

Peptizyde™ is a trademark of Houston Nutraceuticals, Inc.


Caution: MCT powder is derived from palm/coconut kernel oil.

DO NOT USE if active ulcers or GI bleeding are present.


The production process used to manufacture the enzymes found in this product utilizes fermentation materials that are derived from or contain the allergens listed below.  While these fermentation materials should be either consumed during fermentation or removed from the enzyme during additional enzyme isolation steps, minute traces of these allergens may be left in the final enzyme product.  While these traces are expected to be below the limits of detection for standard ELISA based allergen testing methods, there is no guarantee the complete absence of these following allergens:  (Wheat) Gluten, Soy


These statements have not been evaluated by the FDA. This product is not intended to diagnose, cure, treat, or prevent any disease.