- Bioactive Riboflavin 5'-Phosphate (R-5-P) – Provides riboflavin in its metabolically active R-5-P form alongside standard riboflavin, offering enhanced absorption for those who have difficulty converting riboflavin into its active state.
- Supports Key Enzymatic Function – Riboflavin, as FAD and FMN, is a required cofactor for the MTHFR, MAOA, and GSR enzymes, supporting healthy methylation, neurotransmitter metabolism, and antioxidant enzyme activity.
- Healthy Homocysteine and Methylfolate Levels – Riboflavin supports the enzymatic pathways involved in maintaining healthy homocysteine and methylfolate levels. Riboflavin deficiency can result in high homocysteine levels and low methylfolate levels.
- Glutathione Recycling and Antioxidant Support – As a cofactor for glutathione reductase (GSR), riboflavin helps regenerate glutathione, the body's principal antioxidant, supporting healthy aging and cellular energy production.
- Deficiency Symptoms: Riboflavin deficiency can contribute to high homocysteine, low methylfolate levels, flaky scalp, red or cracked corners of the mouth, hair loss, reproductive issues, and a swollen throat and mouth.
Riboflavin R-5-P is a vegetarian capsule delivering 400 mg of riboflavin (vitamin B2) per serving, combining standard riboflavin with riboflavin 5'-phosphate (R-5-P), its biologically active coenzyme form. R-5-P bypasses the conversion step that some individuals need to activate standard riboflavin, supporting greater bioavailability and cellular utilization. As a required cofactor for the MTHFR, MAOA, and GSR enzymes, riboflavin plays a central role in methylation, neurotransmitter metabolism, and antioxidant recycling — making this formula a targeted option for comprehensive vitamin B2 support.
Suggested Dosage: 1 capsule daily, with or without food or as directed by your healthcare practitoner.
Each capsule contain:
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Supplement Facts |
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Serving size |
1 Capsule |
%DV |
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Servings per container |
60 |
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Riboflavin (as riboflavin and riboflavin 5'-phosphate sodium) |
400 mg |
30,769% |
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* Daily Value not established. |
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Other Ingredients: vegetarian capsule (hypromellose and water), microcrystalline cellulose, ascorbyl palmitate, and silica. |
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This product contains NO dairy, egg, fish, shellfish, tree nuts, peanuts, gluten, soy, or sesame.
These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.










