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Article: The Many Benefits of Sulforaphane

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The Many Benefits of Sulforaphane

Sulforaphane is a compound found in broccoli, broccoli sprouts and broccoli seeds. In research studies, it has been shown to support detoxification, healthy inflammation and oxidative stress levels. It has also been studied in the autism community. Some of the many benefits include NRF2 activation, support of Phase 2 detoxification, as well as healthy cardiovascular, respiratory, mitochondria and memory functioning.

KEY BENEFITS: 

Activates NRF2 - NRF2 is a protein messenger contained in every cell of the body that sends information to the cell's DNA. Its job is to help regulate the work of antioxidant proteins that can help protect against oxidative damage. Pretty important job, right? In fact, sulforaphane is the most potent activator of NRF2.

Supports Phase 2 Detox - Detoxification has 3 phases which occur in the liver. The body is constantly being exposed to toxins each day so ensuring each phase is working effectively is critical for overall health. In Phase 1, the body starts breaking down the toxins and Phase 2 is especially important to ensure the toxin by-products are sufficiently neutralized before they can cause more damage to the body. Phase 3, the last phase, is the actual excretion of the toxins.

Sulforaphane research provides compelling evidence indicating its PROTECTIVE EFFECT against the following health conditions:

  • Cancer
  • Lung diseases
  • Cognitive decline / Alzheimer’s
  • Diabetes
  • Heart disease / high blood pressure

Are all sulforaphane supplements the same?

No, absolutely not! Just as the form and dosing matter, so does how the product is extracted, the quality of raw materials used, and how shelf-stable the product is, to name just a few critical considerations. In the case of sulforaphane, it must be first enzymatically converted by myrosinase into its active form to be effective and gut dysbiosis can further inhibit this conversion. Our formulation preserves myrosinase which results in the highest sulforaphane potential in the body, even in those with impaired gut function!

These are the reasons that our Sulforaphane Activated stands out from the rest:

  •      Uses clean CFO2 patented extraction process
  •      Capsules are delayed release, allowing for optimal absorption.
  •      A 5-year shelf life
  •      NSF Certification and 3rd party tested
  •      Higher potency formula providing 1200 mg sulforaphane/myrosinasm blend and 60 mg of Glucosinate (or Glucoraphanin) per 2 pill dose.

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Suggested Dosage: Take 2 capsules daily or as suggested by your healthcare practitioner.*

*Sulforaphane can act as a mild CYP inhibitor and may possibly affect the metabolism of certain drugs. When taking prescription medication, always check with your physician or pharmacist before starting sulforaphane supplements.

 

Sulforaphane Research Studies

Brain Health

Broccoli Sprout Compound May Restore Brain Chemistry Imbalance Linked to Schizophrenia

Sulforaphane Ameliorates Neurobehavioral Deficits and Protects the Brain From Amyloid β Deposits and Peroxidation in Mice With Alzheimer-Like Lesions

Sulforaphane treatment of autism spectrum disorder (ASD)

Sulforaphane from Broccoli Reduces Symptoms of Autism: A Follow-up Case Series from a Randomized Double-blind Study

Identification of urinary metabolites that correlate with clinical improvements in children with autism treated with sulforaphane from broccoli.

Randomized controlled trial of sulforaphane and metabolite discovery in children with autism spectrum disorder

Sulforaphane as an adjunctive treatment for irritability in children with autism spectrum disorder: A randomized, double-blind, placebo-controlled clinical trial

Sulforaphane: An emerging star in neuroprotection and neurological disease prevention 

General Detox and Immune Support

Rapid and sustainable detoxication of airborne pollutants by broccoli sprout beverage: results of a randomized clinical trial in China

Effect of Broccoli Sprouts and Live Attenuated Influenza Virus on Peripheral Blood Natural Killer Cells: A Randomized, Double-Blind Study

Phytochemical Combination PB125 Activates the Nrf2 Pathway and Induces Cellular Protection against Oxidative Injury

Oral sulforaphane increases Phase II antioxidant enzymes in the human upper airway

Sulforaphane: Its “Coming of Age” as a Clinically Relevant Nutraceutical in the Prevention and Treatment of Chronic Disease

Sulforaphane exhibits in vitro and in vivo antiviral activity against pandemic SARS-CoV-2 and seasonal HCoV-OC43 coronaviruses

Efficacy of broccoli and glucoraphanin in COVID-19: From hypothesis to proof-of-concept with three experimental clinical cases

Cancer

Anticancer Activity of Sulforaphane: The Epigenetic Mechanisms and the Nrf2 Signaling Pathway

The role of Sulforaphane in cancer chemoprevention and health benefits: a mini-review

Multi-targeted prevention of cancer by sulforaphane

Effect of Sulforaphane in Men with Biochemical Recurrence after Radical Prostatectomy

Vegetable and fruit intake after diagnosis and risk of prostate cancer progression 

Randomized Phase II Clinical Trial of Sulforaphane in Former Smokers at High Risk for Lung Cancer

Efficacy and tolerability of sulforaphane in the therapeutic management of cancers: a systematic review of randomized controlled trials

Sulforaphane: An emergent anti-cancer stem cell agent

Diabetes

Sulforaphane reduces hepatic glucose production and improves glucose control in patients with type 2 diabetes

613-P: Preventive Effect of Sulforaphane on Type 2 Diabetes-Induced Diabetic Cardiomyopathy via AMPK-Mediated Activation of Glucose/Lipid Metabolism and Nrf2 Function

Sulforaphane reduces hepatic glucose production and improves glucose control in patients with type 2 diabetes

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