Have you heard about CDP Choline?

Cytidine Diphosphate Choline is an active lipotrope of choline that restores brain levels of Phosphatidylserine, Phosphatidylcholine and Sphingomyelin which are crucial to the function of neurons and the myelin sheath that protects them. It also increases brain levels of key neurotransmitters like acetylcholine (for memory), dopamine (for fine motor control and mood), and norepinephrine (for mental energy). Extensive literature exists on the benefits of CDP Choline when taken for post-stroke brain injury, post-concussion symptoms, age related memory loss, and for some neurodegenerative disease (see below).
Suggested Dosage: Children, take 250 mg 1-2 times daily. Adults, take 500 mg capsules 1-4x daily or as suggested by your healthcare practitioner.
CDP Choline Research Studies
Aging Brain Support
Citicoline improves memory performance in elderly subjects
Efficacy of CDP-choline in the treatment of senile alterations in memory
Citicoline improves verbal memory in aging
Effects of cytidine diphosphate choline on rats with memory deficits
Concussion/TBI

Treatment of postconcussional symptoms with CDP-choline
CDP-choline: pharmacological and clinical review
Effects of CDP-choline Treatment on Neurobehavioral Deficits After TBI and on Hippocampal and Neocortical Acetylcholine Release
Recovery Trajectories and Long-Term Outcomes in Traumatic Brain Injury: A Secondary Analysis of the Phase 3 Citicoline Brain Injury Treatment Clinical Trial
Stroke

Citicoline (CDP-choline): Mechanisms of Action and Effects in Ischemic Brain Injury
Cytidine 5-Diphosphocholine (CDP-Choline) in Stroke and Other CNS Disorders
CDP‐Choline as a Biological Supplement During Neurorecovery: A Focused Review
CDP-choline treatment induces brain plasticity markers expression in experimental animal stroke
Neurodegenerative Disorders
Pivotal role of choline metabolites in remyelination
Citicoline - A Neuroprotector With Proven Effects on Glaucomatous Disease
The Citicoline Study: Citicoline Plus Cholinesterase Inhibitors in Aged Patients Affected with Alzheimer’s Disease Study
Effects of CDP-choline on Cognition and Cerebral Hemodynamics in Patients With Alzheimer's Disease
CDP-choline-induced Blood Histamine Changes in Alzheimer's Disease
Addiction

Citicoline in addictive disorders: a review of the literature
Phospholipase A2 (PLA2) Inhibitor
CDP Choline is shown to be an inhibitor of PLA2 activity. PLA2 stands for Phospholipase A2 and is an enzyme that triggers inflammation in the body. During infection, PLA2 is useful in destroying invading microbes. However, when this becomes chronic as a result of long term infections or other conditions, widespread damage can occur. Elevated PLA2 levels are implicated in MS, cancer, RA, allergies, Crohn's Disease, mental health issues and many other conditions.
Viral Inhibition
Citicoline and COVID-19-Related Cognitive and Other Neurologic Complications
Lung Support
Cytidine 5'-diphosphocholine ameliorates hyperoxic lung injury in a neonatal rat model
[Respiratory function and alveolar biological changes under the effect of CDP-choline in pulmonary interstitial pathology: pulmonary fibrosis and sarcoidosis]
For more information on the health benefits of CDP Choline, click for access to Dr. Shaw's Webinar, "The Case for CDP Choline".




