



Methyl-Mate Methylcobalamin Liquid, 1 oz
Methyl-Mate is an ultra-concentrated liquid vitamin B12 supplement providing 2,500 mcg (104,167% DV) of highly absorbable methylcobalamin per half-dropper serving in a pure, preservative-free formula. Methylcobalamin is the biologically active form of B12 that requires no conversion, making it more effectively absorbed and utilized than other B12 forms for protecting nerve tissue, maintaining myelin sheaths, supporting red blood cell development, and promoting optimal detoxification through glutathione production.
Key Benefits:
- Superior Methylcobalamin Absorption – Features methylcobalamin, the most bioavailable form of vitamin B12 that is directly utilized by the body without requiring metabolic conversion, ensuring optimal absorption especially when administered sublingually for maximum effectiveness in supporting cellular function and nervous system health.
- Essential Nerve Protection and Myelin Maintenance – Provides critical support for protecting nerve tissue and maintaining the myelin sheaths that cover and insulate nerve endings, ensuring proper nerve signal transmission, neurological function, and overall nervous system integrity.
- Supports Detoxification and Glutathione Production – Plays a vital role in glutathione creation, the body's master antioxidant, supporting natural detoxification pathways, reducing oxidative stress, and helping eliminate toxins while promoting overall cellular health and metabolic function.
- Promotes Red Blood Cell Formation and Metabolism – Essential for proper digestion, food absorption, protein synthesis, and anemia prevention while helping metabolize fats and carbohydrates, supporting cell formation and longevity for optimal energy production and overall vitality.
*See disclaimer below.

Quality Testing

Clinically Researched

High-Quality Ingredients
Practitioner Approved
Suggested Use
Why New Beginnings?
Over 20 Years of Specialized Expertise
Since 2003, New Beginnings Nutritionals has been dedicated to providing specialized, professional-quality supplements for individuals and families navigating complex health challenges. Founded by Dr. William Shaw, Ph.D., a renowned biochemist and toxicologist, our company was born from groundbreaking research and a deep commitment to supporting those with autism, neuropsychiatric disorders, and chronic illness.
Science-Backed Formulations You Can Trust
Our products are developed through collaboration with leading physicians, naturopaths, researchers, and healthcare practitioners. Dr. Shaw's pioneering research—including over 32 published articles and books translated into 12 languages—informs every formula we create. This scientific foundation ensures that each supplement is purposefully designed to address real health needs with proven ingredients.
Personalized Support When You Need It
What truly sets us apart is our commitment to education and customer care. Our knowledgeable team, led by co-founder Lori Knowles-Jimenez and consulting physician Dr. Kurt Woeller, D.O., provides personalized guidance to both practitioners and individuals. We offer educational webinars, evidence-based protocols, and hands-on support to help you navigate your health journey with confidence.
A Comprehensive Solution for Complex Needs
Our diverse product line addresses multiple aspects of health including:
- Digestive and gastrointestinal support
- Immune system function
- Detoxification pathways
- Mitochondrial health
- Neurological wellness
- Special dietary requirements
Your Partner in Achieving Optimal Health
Whether you're a healthcare practitioner seeking reliable supplements for your patients or an individual committed to your wellness journey, New Beginnings Nutritionals provides the quality, expertise, and support you need. We're not just selling supplements—we're partnering with you to achieve optimal health through potent, pure, and efficacious nutrition.
Shipping & Returns
Free Shipping on Qualifying Orders
We offer free shipping on domestic orders over $129 — no code needed.
Most orders placed by 12:30 PM CST Monday–Friday ship the same day. Need it faster? Expedited options including UPS 2nd Day Air and Next Day Air are available at checkout so you can choose the speed that works best for you. International shipping is available via DHL to select countries.
Easy 60-Day Returns
Not the right fit? Unopened products with the original seal intact may be returned within 60 days of purchase. Please note that probiotics, refrigerated items, and sale merchandise are non-returnable. A 10% restocking fee applies, and original shipping charges are non-refundable. Simply include a copy of your invoice with your return.
Damaged Items? Contact us right away with photos of the packaging and product, and we'll make it right.
For full details visit our Shipping and Return Policy.
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New Beginnings Nutritionals has been my ‘go-to’ supplement company for my patients for many years now. The main reasons are their high quality and diverse supplement products, but also their top-notch support staff who can assist with questions, ordering, etc. I highly recommend New Beginnings Nutritionals as supplement distribution company to work with.
Your products have been life changing for my child with a neurodevelopmental disorder. We have been consistently taking your supplements since October. My son has made so many positive changes in behavior, speech, and social skills. Thank you!
Your great supplements and caring staff give me a peace of mind every time I place an order. As a mom life, is always busy so being able to order high quality supplements from one place versus driving from store to store is a huge time-saver. Thank you New Beginning Nutritionals!
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The information you need from the leading experts in the field of integrative medicine. New Beginnings Nutritionals is committed to bringing high-quality educational resources to our customers. Don't miss out on hearing from Dr. Shaw and other thought leaders – view our extensive library of resources.
